The Effect of Urine pH and Urinary Uric Acid Levels on the Development of Contrast Nephropathy

• Main Authors: Gamze Aslan (Author), Baris Afsar (Author), Alan A. Sag (Author), Volkan Camkiran (Author), Nihan Erden (Author), Sezen Yilmaz (Author), Dimitrie Siriopol (Author), Said Incir (Author), Zhiying You (Author), Miguel L. Garcia (Author), Adrian Covic (Author), David Z.I. Cherney (Author), Richard J. Johnson (Author), Mehmet Kanbay (Author)
• Format: Book
• Published: Karger Publishers, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Hyperuricemia may cause acute kidney injury by activating inflammatory, pro-oxidative and vasoconstrictive pathways. In addition, radiocontrast causes an acute uricosuria, potentially leading to crystal formation. We therefore aimed to investigate the effect of urine acidity and urine ur...