Alterations in germinal center formation and B cell activation during severe Orientia tsutsugamushi infection in mice.

• Main Authors: Casey Gonzales (Author), Yuejin Liang (Author), James Fisher (Author), Galen Card (Author), Jiaren Sun (Author), Lynn Soong (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Scrub typhus is a poorly studied but life-threatening disease caused by the intracellular bacterium Orientia tsutsugamushi (Ot). Cellular and humoral immunity in Ot-infected patients is not long-lasting, waning as early as one-year post-infection; however, its underlying mechanisms remain unclear. T...