Mutational topography reflects clinical neuroblastoma heterogeneity

• Main Authors: Elias Rodriguez-Fos (Author), Mercè Planas-Fèlix (Author), Martin Burkert (Author), Montserrat Puiggròs (Author), Joern Toedling (Author), Nina Thiessen (Author), Eric Blanc (Author), Annabell Szymansky (Author), Falk Hertwig (Author), Naveed Ishaque (Author), Dieter Beule (Author), David Torrents (Author), Angelika Eggert (Author), Richard P. Koche (Author), Roland F. Schwarz (Author), Kerstin Haase (Author), Johannes H. Schulte (Author), Anton G. Henssen (Author)
• Format: Book
• Published: Elsevier, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary: Neuroblastoma is a pediatric solid tumor characterized by strong clinical heterogeneity. Although clinical risk-defining genomic alterations exist in neuroblastomas, the mutational processes involved in their generation remain largely unclear. By examining the topography and mutational sign...