Effects of structurally distinct human HDAC6 and HDAC6/HDAC8 inhibitors against S. mansoni larval and adult worm stages.

• मुख्य लेखकों: Roberto Gimmelli (लेखक), Giuliana Papoff (लेखक), Fulvio Saccoccia (लेखक), Cristiana Lalli (लेखक), Sandra Gemma (लेखक), Giuseppe Campiani (लेखक), Giovina Ruberti (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Public Library of Science (PLoS), 2024-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Schistosomiasis is a major neglected parasitic disease that affects more than 240 million people worldwide caused by Platyhelminthes of the genus Schistosoma. The treatment of schistosomiasis relies on the long-term application of a single safe drug, praziquantel (PZQ). Unfortunately, PZQ is very ef...