Effects of structurally distinct human HDAC6 and HDAC6/HDAC8 inhibitors against S. mansoni larval and adult worm stages.

• Auteurs principaux: Roberto Gimmelli (Auteur), Giuliana Papoff (Auteur), Fulvio Saccoccia (Auteur), Cristiana Lalli (Auteur), Sandra Gemma (Auteur), Giuseppe Campiani (Auteur), Giovina Ruberti (Auteur)
• Format: Livre
• Publié: Public Library of Science (PLoS), 2024-02-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Schistosomiasis is a major neglected parasitic disease that affects more than 240 million people worldwide caused by Platyhelminthes of the genus Schistosoma. The treatment of schistosomiasis relies on the long-term application of a single safe drug, praziquantel (PZQ). Unfortunately, PZQ is very ef...