A phase 1 study of dimdazenil to evaluate the pharmacokinetics, food effect and safety in Chinese healthy subjects

• Main Authors: Fei Wang (Author), Jingjing He (Author), Yanling Zhou (Author), Lijun Ye (Author), Bei Li (Author), Zhiyuan Ma (Author), Chunyan Chen (Author), Ruoxi Zhang (Author), Zhaocun Lin (Author), Jinshan Tang (Author), Zhiping Jin (Author), Yu Jiang (Author), Nengming Lin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and objective: As a partial positive allosteric modulator of the gamma-aminobutyric acid A (GABAA) receptor, dimdazenil was used for the treatment of insomnia with the potential to alleviate associated side effects compared to full agonists. The objective of this trial is to assess the sa...