Exploring the pharmacological mechanisms of Shuanghuanglian against T-cell acute lymphoblastic leukaemia through network pharmacology combined with molecular docking and experimental validation

• Main Authors: You Yang (Author), Yan Yang (Author), Yunfu Shen (Author), Jing Liu (Author), Yan Zeng (Author), Chengming Wei (Author), Chunyan Liu (Author), Yansha Pan (Author), Qulian Guo (Author), Fangfang Zhong (Author), Ling Guo (Author), Wenjun Liu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AbstractContext Due to the poor prognosis of T-cell acute lymphoblastic leukaemia (T-ALL), there is an urgent need to identify safer and more cost-effective drugs.Objective This study evaluated the antitumour activity of Shuanghuanglian (SHL) on T-ALL cells and elucidated the mechanism.Materials and...