Evaluation of novel epibatidine analogs in the rat nicotine drug discrimination assay and in the rat chronic constriction injury neuropathic pain model

• Main Authors: Kevin Luque-Sanchez (Author), Jasmine Felix (Author), Joshua Bilbrey (Author), Luis Restrepo (Author), Morgan Reeves (Author), Lance R. McMahon (Author), Jenny L. Wilkerson (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nicotine is the primary psychoactive component responsible for maintaining tobacco dependence in humans. Chronic pain is often a consequence of tobacco-related pathologies, and the development of a dual therapeutic that could treat chronic pain and tobacco dependence would be advantageous. Epibatidi...