Methodological Challenges of Digital PCR Detection of the Histone H3 K27M Somatic Variant in Cerebrospinal Fluid

• Main Authors: Margarita Zaytseva (Author), Natalia Usman (Author), Ekaterina Salnikova (Author), Agunda Sanakoeva (Author), Andge Valiakhmetova (Author), Almira Chervova (Author), Ludmila Papusha (Author), Galina Novichkova (Author), Alexander Druy (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cell-free DNA (cfDNA) in body fluids is invaluable for cancer diagnostics. Despite the impressive potential of liquid biopsies for the diagnostics of central nervous system (CNS) tumors, a number of challenges prevent introducing this approach into routine laboratory practice. In this study, we adop...