Innovative Strategies to Develop Chemical Categories Using a Combination of Structural and Toxicological Properties

• Main Authors: Monika Batke (Author), Martin Gütlein (Author), Falko Partosch (Author), Ursula Gundert-Remy (Author), Christoph Helma (Author), Stefan Kramer (Author), Andreas Maunz (Author), Madeleine Seeland (Author), Annette Bitsch (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

1.AbstractInterest is increasing in the development of non-animal methods for toxicological evaluations. These methods are however, particularly challenging for complex toxicological endpoints such as repeated dose toxicity. European Legislation, e.g. the European Union´s Cosmetic Directive and REAC...