Desensitization of delayed-type hypersensitivity in mice: suppressive environment

• Main Authors: Takashi Katsura (Author), Kazuo Kobayashi (Author), Michio Hosaka (Author), Sachiko Sugihara (Author), Tsuyoshi Kasama (Author), Keita Kasahara (Author), Stanley Cohen (Author), Takeshi Yoshida (Author)
• Format: Book
• Published: Hindawi Limited, 1993-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The systemic injection of high doses of antigen into a preimmunized animal results in transient unresponsiveness of cell-mediated immune responses. This phenomenon is known as desensitization. Serum interleukin 2 (IL-2) activity was found transiently in desensitized mice at 3 h after the antigen cha...