Computational Investigations of Traditional Chinese Medicinal Compounds against the Omicron Variant of SARS-CoV-2 to Rescue the Host Immune System

• Главные авторы: Ziad Tareq Naman (Автор), Salim Kadhim (Автор), Zahraa J. K. Al-Isawi (Автор), Christopher J. Butch (Автор), Ziyad Tariq Muhseen (Автор)
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• Опубликовано: MDPI AG, 2022-06-01T00:00:00Z.
• Предметы: article
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Macrodomain-I of the NSP3 (non-structural protein 3) is responsible for immune response hijacking in the SARS-CoV-2 infection known as COVID-19. In the omicron variant (B.1.1.529), this domain harbors a new mutation, V1069I, which may increase the binding of ADPr and consequently the infection sever...