Association between genetic variants and development of antibodies to infliximab: A cross-sectional study in Chinese patients with Crohn's disease

• Main Authors: Kouzhu Zhu (Author), Xiaoliang Ding (Author), Zhiyao Chen (Author), Qinhua Xi (Author), Xueqin Pang (Author), Weichang Chen (Author), Liyan Miao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aims: Genetic variants increase the susceptibility to anti-drug antibodies (ADA) in response to anti-TNF therapy in chronic inflammatory diseases. However, little is known about genetic variants in Chinese populations. This study aimed to identify genetic variants contributing to the risk of the dev...