Early Resuscitation in Paediatric Sepsis Using Inotropes - A Randomised Controlled Pilot Study in the Emergency Department (RESPOND ED): Study Protocol and Analysis Plan

• Main Authors: Amanda Harley (Author), Shane George (Author), Megan King (Author), Natalie Phillips (Author), Gerben Keijzers (Author), Debbie Long (Author), Kristen Gibbons (Author), Rinaldo Bellomo (Author), Luregn J. Schlapbach (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Septic shock in children still carries substantial mortality and morbidity. While resuscitation with 40-60 mL/kg intravenous fluid boluses remains a cornerstone of initial resuscitation, an increasing body of evidence indicates potential for harm related to high volume fluid administra...