Targeting Siderophore-Mediated Iron Uptake in <i>M. abscessus</i>: A New Strategy to Limit the Virulence of Non-Tuberculous Mycobacteria

• Main Authors: Matteo Mori (Author), Giovanni Stelitano (Author), Giulia Cazzaniga (Author), Arianna Gelain (Author), Andrea Tresoldi (Author), Mario Cocorullo (Author), Martina Roversi (Author), Laurent R. Chiarelli (Author), Martina Tomaiuolo (Author), Pietro Delre (Author), Giuseppe F. Mangiatordi (Author), Anna Griego (Author), Loris Rizzello (Author), Alberto Cassetta (Author), Sonia Covaceuszach (Author), Stefania Villa (Author), Fiorella Meneghetti (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Targeting pathogenic mechanisms, rather than essential processes, represents a very attractive approach for the development of new antimycobacterial drugs. In this context, iron acquisition routes have recently emerged as potentially druggable pathways. However, the importance of siderophore biosynt...