A highly neutralizing human monoclonal antibody targeting a novel linear epitope on staphylococcal enterotoxin B

• Main Authors: Hongyin Fan (Author), Liqun Zhao (Author), Weiwei Wang (Author), Feng Yu (Author), Haiming Jing (Author), Yun Yang (Author), Xiaoli Zhang (Author), Zhuo Zhao (Author), Qiang Gou (Author), Weijun Zhang (Author), Quanming Zou (Author), Jinyong Zhang (Author), Hao Zeng (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Staphylococcal Enterotoxin B (SEB), produced by Staphylococcus aureus (S. aureus), is a powerful superantigen that induces severe immune disruption and toxic shock syndrome (TSS) upon binding to MHC-II and TCR. Despite its significant impact on the pathogenesis of S. aureus, there are currently no s...