Blood pressure signature genes and blood pressure response to thiazide diuretics: results from the PEAR and PEAR-2 studies

• Main Authors: Ana Caroline C. Sá (Author), Amy Webb (Author), Yan Gong (Author), Caitrin W. McDonough (Author), Mohamed H. Shahin (Author), Somnath Datta (Author), Taimour Y. Langaee (Author), Stephen T. Turner (Author), Amber L. Beitelshees (Author), Arlene B. Chapman (Author), Eric Boerwinkle (Author), John G. Gums (Author), Steven E. Scherer (Author), Rhonda M. Cooper-DeHoff (Author), Wolfgang Sadee (Author), Julie A. Johnson (Author)
• Format: Book
• Published: BMC, 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Recently, 34 genes had been associated with differential expression relative to blood pressure (BP)/ hypertension (HTN). We hypothesize that some of the genes associated with BP/HTN are also associated with BP response to antihypertensive treatment with thiazide diuretics. Method...