Effects of Bardoxolone Methyl on Hepatic Enzymes in Patients with Type 2 Diabetes Mellitus and Stage 4 CKD

Effects of Bardoxolone Methyl on Hepatic Enzymes in Patients with Type 2 Diabetes Mellitus and Stage 4 CKD

In a multinational placebo‐controlled phase III clinical trial in 2,185 patients with type 2 diabetes mellitus and stage 4 chronic kidney disease, treatment with the Nrf2 activator bardoxolone methyl increased estimated glomerular filtration rate, a measure of kidney function, but also resulted in i...

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Main Authors: James H. Lewis (Author), Michel Jadoul (Author), Geoffrey A. Block (Author), Melanie P. Chin (Author), Deborah A. Ferguson (Author), Angie Goldsberry (Author), Colin J. Meyer (Author), Megan O'Grady (Author), Pablo E. Pergola (Author), Scott A. Reisman (Author), W. Christian Wigley (Author), Glenn M. Chertow (Author)
Format: Book
Published: Wiley, 2021-01-01T00:00:00Z.
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