Multidrug Resistance Modulation Activity of Silybin Derivatives and Their Anti-Inflammatory Potential

• Main Authors: Simona Dobiasová (Author), Kateřina Řehořová (Author), Denisa Kučerová (Author), David Biedermann (Author), Kristýna Káňová (Author), Lucie Petrásková (Author), Kamila Koucká (Author), Radka Václavíková (Author), Kateřina Valentová (Author), Tomáš Ruml (Author), Tomáš Macek (Author), Vladimír Křen (Author), Jitka Viktorová (Author)
• Format: Book
• Published: MDPI AG, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Silybin is considered to be the main biologically active component of silymarin. Its oxidized derivative 2,3-dehydrosilybin typically occurs in silymarin in small, but non-negligible amounts (up to 3%). Here, we investigated in detail complex biological activities of silybin and 2,3-dehydrosilybin o...