Absence of medication-related jaw osteonecrosis after treatment with strontium ranelate in ovariectomized rats

• Main Authors: Leomar Emanuel de Almeida MECCA (Author), Amanda Regina FISCHBORN (Author), Jessica Daniela ANDREIS (Author), Gabrielle DELFRATE (Author), Tayline MROCZEK (Author), Natália Mariane RIGO (Author), Fábio Brasil de OLIVEIRA (Author), Myrella Lessio CASTRO (Author), Mario TABA JUNIOR (Author), Marcela CLAUDINO (Author), Gilson Cesar Nobre FRANCO (Author)
• Formato: Libro
• Publicado: Sociedade Brasileira de Pesquisa Odontológica, 2022-06-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Abstract This study aimed to evaluate the potential of strontium ranelate (SR) in medication-related jaw osteonecrosis (MRONJ) after tooth extraction in ovariectomized rats. Thirty ovariectomized rats were divided into three groups (n = 10): bisphophonate (BP) group (zoledronic acid; 0.4 mg/kg/week)...