The BCL2/BAX/ROS pathway is involved in the inhibitory effect of astragaloside IV on pyroptosis in human umbilical vein endothelial cells

Context Astragaloside IV (AS-IV) is extracted from Astragalus membranaceus (Fisch.) Bunge (Fabaceae). However, its effects on endothelial cell injury remain unclear.Objective To investigate the mechanisms underlying the effects of AS-IV on lipopolysaccharide (LPS)-induced endothelial injury in vitro...

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Main Authors: Yi Su (Author), Xin Yin (Author), Xin Huang (Author), Qianqian Guo (Author), Mingyuan Ma (Author), Liheng Guo (Author)
Format: Book
Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
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