Defining the right diluent for intravenous infusion of therapeutic antibodies

• Main Authors: Shen Luo (Author), Keisha Melodi McSweeney (Author), Tao Wang (Author), Silvia M. Bacot (Author), Gerald M. Feldman (Author), Baolin Zhang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Therapeutic monoclonal antibodies (mAbs) are commonly administered to patients through intravenous (IV) infusion, which involves diluting the medication into an infusion solution (e.g., saline and 5% dextrose). Using the wrong diluent can cause product aggregation, which may compromise patient safet...