The inhibitory effect and mechanism of Yi-qi-hua-yu-jie-du decoction on the drug resistance of gastric cancer stem cells based on ABC transporters

• Main Authors: Wenjie Huang (Author), Fang Wen (Author), Peixing Gu (Author), Jiatong Liu (Author), Yun Xia (Author), Ye Li (Author), Jiayu Zhou (Author), Siyuan Song (Author), Shuai Ruan (Author), Suping Gu (Author), Xiaoxue Chen (Author), Peng Shu (Author)
• Format: Book
• Published: BMC, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The drug resistance of tumor stem cells is an obstacle in gastric cancer (GC) treatment and the high expression of ABC transporters is a classic reason for drug resistance. This study aimed to construct a reliable GC drug-resistant stem cell model and explore the inhibitory effec...