FROG INTESTINAL PERFUSION TO EVALUATE DRUG PERMEABILITY: APPLICATION TO P-gp AND CYP3A4 SUBSTRATES
AbstractTo evaluate the reliability of using in situ frog intestinal perfusion technique for permeability assessment of carrier transported drugs which are also substrates for CYP enzymes. Single Pass Intestinal Perfusion (SPIP) studies were performed in frogs of the species Rana tigrina using estab...
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| Main Authors: | , , |
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| Format: | Book |
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Frontiers Media S.A.,
2015-07-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |