Synthesis of novel substituted N-aryl benzamides as hA3G stabilizers and their inhibitory activities against hepatitis C virus replication

• Những tác giả chính: Yanping Li (Tác giả), Zonggen Peng (Tác giả), Lanhu Hao (Tác giả), Zhouyi Wu (Tác giả), Yanping Zhu (Tác giả), Laixing Hu (Tác giả), Jiandong Jiang (Tác giả), Zhuorong Li (Tác giả)
• Định dạng: Sách
• Được phát hành: Elsevier, 2013-09-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

A series of novel amino-substituted N-aryl benzamide analogs were synthesized and evaluated for their ability to inhibit hepatitis C virus (HCV) replication in acutely infected Huh7.5 cells. Most of the substituted N-aryl benzamide compounds showed convincing anti-HCV activities. Compounds 1f, 1g an...