Synthesis of 3,4-Dihydropyrimidin(thio)one Containing Scaffold: Biginelli-like Reactions

• Main Authors: Francisco Sánchez-Sancho (Author), Marcos Escolano (Author), Daniel Gaviña (Author), Aurelio G. Csáky (Author), María Sánchez-Roselló (Author), Santiago Díaz-Oltra (Author), Carlos del Pozo (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The interest in 3,4-dihydropyrimidine-2(1<i>H</i>)-(thio)ones is increasing every day, mainly due to their paramount biological relevance. The Biginelli reaction is the classical approach to reaching these scaffolds, although the product diversity suffers from some limitations. In order...