Enhancement of the Oral Bioavailability of Fexofenadine Hydrochloride via Cremophor® El-Based Liquisolid Tablets

• Main Authors: Soad Ali Yehia (Author), Mohamed Shafik El-Ridi (Author), Mina Ibrahim Tadros (Author), Nolwa Gamal El-Sherif (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2015-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: The current work aimed to develop promising Fexofenadine hydrochloride (FXD) liquisolid tablets able to increase its oral bioavailability and shorten time to reach maximum plasma concentrations (Tmax). Methods: Eighteen liquisolid powders were developed based on 3 variables; (i) vehicle typ...