Adenosine Receptor Agonists Increase the Inhibition of Platelet Function by P2Y₁₂ Antagonists in a cAMP- and Calcium-Dependent Manner

• Main Authors: Nina Wolska (Author), Hassan Kassassir (Author), Boguslawa Luzak (Author), Cezary Watala (Author), Marcin Rozalski (Author)
• Format: Book
• Published: MDPI AG, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We have shown previously that platelet activity can be lowered through the simultaneous inhibition of P2Y₁₂ receptor and activation of adenosine receptors (AR). This work explores this concept by testing the antiplatelet potential of nine AR agonists in combination with P2Y<...