Long-lasting memory deficits in mice withdrawn from cocaine are concomitant with neuroadaptations in hippocampal basal activity, GABAergic interneurons and adult neurogenesis

• Autores principales: David Ladrón de Guevara-Miranda (Autor), Carmelo Millón (Autor), Cristina Rosell-Valle (Autor), Mercedes Pérez-Fernández (Autor), Michele Missiroli (Autor), Antonia Serrano (Autor), Francisco J. Pavón (Autor), Fernando Rodríguez de Fonseca (Autor), Magdalena Martínez-Losa (Autor), Manuel Álvarez-Dolado (Autor), Luis J. Santín (Autor), Estela Castilla-Ortega (Autor)
• Formato: Libro
• Publicado: The Company of Biologists, 2017-03-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Cocaine addiction disorder is notably aggravated by concomitant cognitive and emotional pathology that impedes recovery. We studied whether a persistent cognitive/emotional dysregulation in mice withdrawn from cocaine holds a neurobiological correlate within the hippocampus, a limbic region with a k...