Molecular targets and mechanisms of Sijunzi decoction in the treatment of Parkinson's disease: evidence from network pharmacology, molecular docking, molecular dynamics simulation, and experimental validation

• Główni autorzy: Yang Jiang (Autor), Wanfeng Wu (Autor), Le Xie (Autor), Yue Zhou (Autor), Kailin Yang (Autor), Dahua Wu (Autor), Wenfeng Xu (Autor), Rui Fang (Autor), Jinwen Ge (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2024-11-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

AimTo explore the molecular mechanism of Sijunzi Decoction (SJZD) in the treatment of Parkinson's disease (PD) through the application of network pharmacology, molecular docking, and molecular dynamics simulations, complemented by experimental verification.MethodsThe BATMAN-TCM, GeneCards, and...