Therapeutic potential of mitochondrial uncouplers for the treatment of metabolic associated fatty liver disease and NASH

Background: Mitochondrial uncouplers shuttle protons across the inner mitochondrial membrane via a pathway that is independent of adenosine triphosphate (ATP) synthase, thereby uncoupling nutrient oxidation from ATP production and dissipating the proton gradient as heat. While initial toxicity conce...

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Bibliographic Details
Main Authors: Leigh Goedeke (Author), Gerald I. Shulman (Author)
Format: Book
Published: Elsevier, 2021-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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