Navigating bioactivity space in anti-tubercular drug discovery through the deployment of advanced machine learning models and cheminformatics tools: a molecular modeling based retrospective study

• Main Authors: Ratul Bhowmik (Author), Ravi Kant (Author), Ajay Manaithiya (Author), Daman Saluja (Author), Bharti Vyas (Author), Ranajit Nath (Author), Kamal A. Qureshi (Author), Seppo Parkkila (Author), Ashok Aspatwar (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mycobacterium tuberculosis is the bacterial strain that causes tuberculosis (TB). However, multidrug-resistant and extensively drug-resistant tuberculosis are significant obstacles to effective treatment. As a result, novel therapies against various strains of M. tuberculosis have been developed. Dr...