Fluorescein-Labeled Thiacalix[4]arenes as Potential Theranostic Molecules: Synthesis, Self-Association, and Antitumor Activity

• Main Authors: Alan Akhmedov (Author), Olga Terenteva (Author), Evgenia Subakaeva (Author), Pavel Zelenikhin (Author), Ramilia Shurpik (Author), Dmitriy Shurpik (Author), Pavel Padnya (Author), Ivan Stoikov (Author)
• Format: Book
• Published: MDPI AG, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this paper, a series of thiacalix[4]arenes were synthesized as potential theranostic molecules for antitumor therapy. We propose an original strategy for the regioselective functionalization of thiacalix[4]arene with a fluorescent label to obtain antiangiogenic agent mimetics. The aggregation pro...