Fluorescein-Labeled Thiacalix[4]arenes as Potential Theranostic Molecules: Synthesis, Self-Association, and Antitumor Activity

• Váldodahkkit: Alan Akhmedov (Dahkki), Olga Terenteva (Dahkki), Evgenia Subakaeva (Dahkki), Pavel Zelenikhin (Dahkki), Ramilia Shurpik (Dahkki), Dmitriy Shurpik (Dahkki), Pavel Padnya (Dahkki), Ivan Stoikov (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2022-10-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

In this paper, a series of thiacalix[4]arenes were synthesized as potential theranostic molecules for antitumor therapy. We propose an original strategy for the regioselective functionalization of thiacalix[4]arene with a fluorescent label to obtain antiangiogenic agent mimetics. The aggregation pro...