Fluorescein-Labeled Thiacalix[4]arenes as Potential Theranostic Molecules: Synthesis, Self-Association, and Antitumor Activity

• Principais autores: Alan Akhmedov (Autor), Olga Terenteva (Autor), Evgenia Subakaeva (Autor), Pavel Zelenikhin (Autor), Ramilia Shurpik (Autor), Dmitriy Shurpik (Autor), Pavel Padnya (Autor), Ivan Stoikov (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2022-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

In this paper, a series of thiacalix[4]arenes were synthesized as potential theranostic molecules for antitumor therapy. We propose an original strategy for the regioselective functionalization of thiacalix[4]arene with a fluorescent label to obtain antiangiogenic agent mimetics. The aggregation pro...