Butyrate-treatment induces gingival epithelial cell death in a three-dimensional gingival-connective tissue hybrid co-culture system

• Egile Nagusiak: Yusuke Kurosawa (Egilea), Hirofumi Yamaguchi (Egilea), Kazuki Uemichi (Egilea), Keiji Shinozuka (Egilea), Yuki Kirihara (Egilea), Hiromasa Tsuda (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2023-04-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Three-dimensional (3D) cell culture systems are reported to be more physiologically similar to the in vivo state than 2-dimensional (2D) models, which are extensively employed in periodontal research. Herein, we developed a 3D gingival tissue model with both epithelial and lamina propria layers usin...