LEAP2 Impairs the Capability of the Growth Hormone Secretagogue Receptor to Regulate the Dopamine 2 Receptor Signaling

• Autori principali: Emilio R. Mustafá (Autore), Santiago Cordisco González (Autore), Marjorie Damian (Autore), Sonia Cantel (Autore), Severine Denoyelle (Autore), Renaud Wagner (Autore), Helgi B. Schiöth (Autore), Jean-Alain Fehrentz (Autore), Jean-Louis Banères (Autore), Mario Perelló (Autore), Jesica Raingo (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

The growth hormone secretagogue receptor (GHSR) signals in response to ghrelin, but also acts via ligand-independent mechanisms that include either constitutive activation or interaction with other G protein-coupled receptors, such as the dopamine 2 receptor (D2R). A key target of GHSR in neurons is...