The direct STAT3 inhibitor 6-ethoxydihydrosanguinarine exhibits anticancer activity in gastric cancer

• Main Authors: Xuewen Liu (Author), Xin Jin (Author), Hongling Ou (Author), Chen Qian (Author), Hui Wu (Author), Chunmei Zuo (Author), Yuliang Ren (Author), Miaoxin Fu (Author), Te Zhang (Author), Liang Zhang (Author), Yuan Si (Author), Ying Liu (Author)
• Format: Book
• Published: Compuscript Ltd, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Signal transducer and activator of transcription 3 (STAT3) plays a key role in promoting tumor malignant progression. Suppression of hyperactivated STAT3 signaling has emerged as a potential therapeutic strategy for many cancer types. In this study, the effect of 6-ethoxydihydrosanguinarine (6-EDS),...