Exploiting the DNA Damaging Activity of Liposomal Low Dose Cytarabine for Cancer Immunotherapy

• Main Authors: Jordan D. Lewicky (Author), Alexandrine L. Martel (Author), Nya L. Fraleigh (Author), Emilie Picard (Author), Leila Mousavifar (Author), Arnaldo Nakamura (Author), Francisco Diaz-Mitoma (Author), René Roy (Author), Hoang-Thanh Le (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Perhaps the greatest limitation for the continually advancing developments in cancer immunotherapy remains the immunosuppressive tumor microenvironment (TME). The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) axis is an emerging immunotherapy target, with the resulting type I...