Systemic TNFα correlates with residual β-cell function in children and adolescents newly diagnosed with type 1 diabetes

• Egile Nagusiak: Anne Julie Overgaard (Egilea), Jens Otto Broby Madsen (Egilea), Flemming Pociot (Egilea), Jesper Johannesen (Egilea), Joachim Størling (Egilea)
• Formatua: Liburua
• Argitaratua: BMC, 2020-09-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract Background Type 1 diabetes (T1D) is caused by immune-mediated destruction of the β-cells. After initiation of insulin therapy many patients experience a period of improved residual β-cell function leading to partial disease remission. Cytokines are important immune-modulatory molecules and...