Long non-coding RNA lnc-CHAF1B-3 promotes renal interstitial fibrosis by regulating EMT-related genes in renal proximal tubular cells

• Main Authors: Kentaro Imai (Author), Takuji Ishimoto (Author), Tomohito Doke (Author), Toshiki Tsuboi (Author), Yu Watanabe (Author), Keisuke Katsushima (Author), Miho Suzuki (Author), Hideto Oishi (Author), Kazuhiro Furuhashi (Author), Yasuhiko Ito (Author), Yutaka Kondo (Author), Shoichi Maruyama (Author)
• Format: Book
• Published: Elsevier, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Renal interstitial fibrosis (RIF) is a common pathological manifestation of chronic kidney diseases. Epithelial-mesenchymal transition (EMT) of tubular epithelial cells is considered a major cause of RIF. Although long non-coding RNAs (lncRNAs) are reportedly involved in various pathophysiological p...