Apoc2 loss-of-function zebrafish mutant as a genetic model of hyperlipidemia

• Үндсэн зохиолчид: Chao Liu (Зохиогч), Keith P. Gates (Зохиогч), Longhou Fang (Зохиогч), Marcelo J. Amar (Зохиогч), Dina A. Schneider (Зохиогч), Honglian Geng (Зохиогч), Wei Huang (Зохиогч), Jungsu Kim (Зохиогч), Jennifer Pattison (Зохиогч), Jian Zhang (Зохиогч), Joseph L. Witztum (Зохиогч), Alan T. Remaley (Зохиогч), P. Duc Dong (Зохиогч), Yury I. Miller (Зохиогч)
• Формат: Ном
• Хэвлэсэн: The Company of Biologists, 2015-08-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Apolipoprotein C-II (APOC2) is an obligatory activator of lipoprotein lipase. Human patients with APOC2 deficiency display severe hypertriglyceridemia while consuming a normal diet, often manifesting xanthomas, lipemia retinalis and pancreatitis. Hypertriglyceridemia is also an important risk factor...