Synthesis, kinetic studies and in-silico investigations of novel quinolinyl-iminothiazolines as alkaline phosphatase inhibitors

• Main Authors: Muhammad Naeem Mustafa (Author), Pervaiz Ali Channar (Author), Muhammad Sarfraz (Author), Aamer Saeed (Author), Syeda Abida Ejaz (Author), Mubashir Aziz (Author), Fatmah Ali Alasmary (Author), Hanadi Yaqob Alsoqair (Author), Hussain Raza (Author), Song Ja Kim (Author), Asad Hamad (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Deposition of hydroxyapatite (HA) or alkaline phosphate crystals on soft tissues causes the pathological calcification diseases comprising of end-stage osteoarthritis (OA), ankylosing spondylitis (AS), medial artery calcification and tumour calcification. The pathological calcification is symbolised...