Intact Cell Binding for In Vitro Prediction of Sedative and Non-sedative Histamine H1-Receptor Antagonists Based on Receptor Internalization
We evaluated changes in the binding properties of sedative and non-sedative histamine H1-receptor antagonists induced by internalization of H1 receptors in intact human U373 MG astrocytoma cells. Internalization of H1 receptors was induced without their degradation by treatment with 0.1 mM histamine...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2008-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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Internet
Connect to this object online.3rd Floor Main Library
| Call Number: |
A1234.567 |
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| Copy 1 | Available |