miR-424/322 protects against abdominal aortic aneurysm formation by modulating the Smad2/3/runt-related transcription factor 2 axis

• Main Authors: Hsiao-Ya Tsai (Author), Jen-Chun Wang (Author), Yu-Juei Hsu (Author), Yi-Lin Chiu (Author), Chih-Yuan Lin (Author), Cheng-Yo Lu (Author), Shih-Hung Tsai (Author)
• Format: Book
• Published: Elsevier, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rupture of abdominal aortic aneurysms (AAAs) is one of the leading causes of sudden death in the elderly population. The osteogenic transcription factor runt-related gene (RUNX) encodes multifunctional mediators of intracellular signal transduction pathways in vascular remodeling and inflammation. W...