Genotype frequencies of polymorphic MDR1 variants in the Kazakhstani population

• मुख्य लेखकों: Samat Kozhakhmetov (लेखक), Adil Supiyev (लेखक), Almagul Kushugulova (लेखक), Indira Tynybayeva (लेखक), Alibek Kossumov (लेखक), Leila Utepova (लेखक), Saule Saduakhasova (लेखक), Gulnara Shakhabayeva (लेखक), Talgat Nurgozhin (लेखक), Zhaxybay Zhumadilov (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: University Library System, University of Pittsburgh, 2014-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Introduction: Statins appear to be handled by an ATP-dependent membrane transporter and three SNPs (C1236T (rs1128503), G2677T (rs2032582), and C3435T (rs1045642), which capture the common genetic variation at this locus. Individuals, who carry the T allele at each SNP (i.e., the T-T-T haplotype), h...