Highlighting Interleukin-36 Signalling in Plaque Psoriasis and Pustular Psoriasis

• Main Authors: Kazuhisa Furue (Author), Kazuhiko Yamamura (Author), Gaku Tsuji (Author), Chikage Mitoma (Author), Hiroshi Uchi (Author), Takeshi Nakahara (Author), Makiko Kido-Nakahara (Author), Takafumi Kadono (Author), Masutaka Furue (Author)
• Format: Book
• Published: Medical Journals Sweden, 2017-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Plaque psoriasis and pustular psoriasis are overlapping, but distinct, disorders. The therapeutic response to biologics supports the pivotal role of the tumour necrosis alpha (TNF-?)/ interleukin (IL)-23/IL-17/IL-22 axis in the pathogenesis of these disorders. Recently, functional activation of the...