Anti-Inflammatory Cytokine Interleukin-4 Inhibits Inducible Nitric Oxide Synthase Gene Expression in the Mouse Macrophage Cell Line RAW264.7 through the Repression of Octamer-Dependent Transcription

Inducible nitric oxide synthase (iNOS) is a signature molecule involved in the classical activation of M1 macrophages and is induced by the Nos2 gene upon stimulation with Th1-cell derived interferon-gamma (IFNγ) and bacterial lipopolysaccharide (LPS). Although the anti-inflammatory cytokine IL-4 is...

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Main Authors: Miki Hiroi (Author), Yoshiichi Sakaeda (Author), Hana Yamaguchi (Author), Yoshihiro Ohmori (Author)
Format: Book
Published: Hindawi Limited, 2013-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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