Anti-Inflammatory Cytokine Interleukin-4 Inhibits Inducible Nitric Oxide Synthase Gene Expression in the Mouse Macrophage Cell Line RAW264.7 through the Repression of Octamer-Dependent Transcription

Inducible nitric oxide synthase (iNOS) is a signature molecule involved in the classical activation of M1 macrophages and is induced by the Nos2 gene upon stimulation with Th1-cell derived interferon-gamma (IFNγ) and bacterial lipopolysaccharide (LPS). Although the anti-inflammatory cytokine IL-4 is...

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Bibliografski detalji
Glavni autori: Miki Hiroi (Autor), Yoshiichi Sakaeda (Autor), Hana Yamaguchi (Autor), Yoshihiro Ohmori (Autor)
Format: Knjiga
Izdano: Hindawi Limited, 2013-01-01T00:00:00Z.
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