Phloretic acid requires the insulin/IGF-1 pathway and autophagy to enhance stress resistance and extend the lifespan of Caenorhabditis elegans

• Главные авторы: Bo Li (Автор), Li Dong (Автор), Wei Meng (Автор), Shi-Ying Xiong (Автор), Gui-Sheng Wu (Автор), Wen-Zhe Ma (Автор), Huai-Rong Luo (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Objective: In humans, aging is associated with increased susceptibility to most age-related diseases. Phloretic acid (PA), a naturally occurring compound found in Ginkgo biloba and Asparagus, exhibits has potential as an anti-aging agent and possesses antioxidant, anti-inflammatory, and immunomodula...