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Hemophagocytic syndrome associated with Plasmodium falciparum infection

Hemophagocytic syndrome (HPS) has been associated with infections, hematological malignancies and autoimmune conditions. Malaria is rarely reported to cause HPS. We report a case of an 11-month-old infant with fever, hepatosplenomegaly, pancytopenia, high serum ferritin, hypertriglyceridemia, and bo...

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Bibliographic Details
Main Authors: P N Vinoth (Author), K Abilash Thomas (Author), S Muthamil Selvan (Author), D Febe Renjitha Suman (Author), Julius Xavier Scott (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2011-01-01T00:00:00Z.
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Summary:Hemophagocytic syndrome (HPS) has been associated with infections, hematological malignancies and autoimmune conditions. Malaria is rarely reported to cause HPS. We report a case of an 11-month-old infant with fever, hepatosplenomegaly, pancytopenia, high serum ferritin, hypertriglyceridemia, and bone marrow hemophagocytosis, consistent with hemophagocytic syndrome. Gametocytes of plasmodium falciparum were identified on bone marrow aspiration. Rapid recovery was observed after treatment with antimalarials.
Item Description:0377-4929
10.4103/0377-4929.85105

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