Lipoxin Inhibits Fungal Uptake by Macrophages and Reduces the Severity of Acute Pulmonary Infection Caused by Paracoccidioides brasiliensis

• Main Authors: Laura R. R. Ribeiro (Author), Flávio V. Loures (Author), Eliseu F. de Araújo (Author), Cláudia Feriotti (Author), Tânia A. Costa (Author), Carlos Henrique Serezani (Author), Sonia Jancar (Author), Vera L. G. Calich (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cysteinyl leukotrienes (CysLTs) and lipoxins (LXs) are lipid mediators that control inflammation, with the former inducing and the latter inhibiting this process. Because the role played by these mediators in paracoccidioidomycosis was not investigated, we aimed to characterize the role of CysLT in...