Uterine washings as a novel method for early detection of ovarian cancer: Trials and tribulations

• Main Authors: Tiffany Y. Sia (Author), Zvi Yaari (Author), Ron Feiner (Author), Evan Smith (Author), Arnaud Da Cruz Paula (Author), Pier Selenica (Author), Sital Doddi (Author), Dennis S. Chi (Author), Nadeem R. Abu-Rustum (Author), Douglas A. Levine (Author), Britta Weigelt (Author), Martin Fleisher (Author), Lakshmi V. Ramanathan (Author), Daniel A. Heller (Author), Kara Long Roche (Author)
• Format: Book
• Published: Elsevier, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Given the tubal origin of high-grade serous ovarian cancer (HGSC), we sought to investigate intrauterine lavage (IUL) as a novel method of biomarker detection. IUL and serum samples were collected from patients with HGSC or benign pathology. Although CA-125 and HE4 concentrations were significantly...