Simultaneous determination of ethinyl estradiol and drospirenone in oral contraceptive by high performance liquid chromatography

• Main Authors: Viviane Benevenuti Silva (Author), Angel Arturo Gaona Galdos (Author), Cintia Maria Alves Mothe (Author), Michele Bacchi Pallastrelli (Author), Maria Segunda Aurora Prado (Author), Anil Kumar Singh (Author), Erika Rosa Maria Kedor-Hackmann (Author), Maria Inês Rocha Miritello Santoro (Author)
• Format: Book
• Published: Universidade de São Paulo, 2013-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A simple, rapid, economical and reliable high performance liquid chromatographic method has been developed and successfully applied in simultaneous determination of ethinyl estradiol and drospirenone in coated tablets. The HPLC method was performed on a LiChroCART® 100RP column (125x4 mm i.d., 5 µm)...